DesignRx delivers pharmacy value and service
for your specialty medication needs
  Home  
  Counseling  
  Compounding  
  How to Order  
  Contact Us  

mefloquine

mefloquine

Pronunciation: MEF loe kwin

Brand: Lariam

Lariam 250 mg

round, white, imprinted with LARIAM 250 ROCHE

Image of Lariam 250 mg
slide 1 of 3
    

Mefloquine 250 mg-BAR

oval, white, imprinted with b 171

Image of Mefloquine 250 mg-BAR
slide 2 of 3
    

Mefloquine 250 mg-ROX

round, white, imprinted with 54 111

Image of Mefloquine 250 mg-ROX
slide 3 of 3
    

What is the most important information I should know about mefloquine?

Multum emt

Some people taking mefloquine have had sudden serious psychiatric or nerve problems, some of which lasted long after they stopped taking this medicine. These side effects can be permanent.

Multum calldoc

Stop taking mefloquine and call your doctor right away if have any of these side effects: headache, ringing in your ears, dizziness, loss of balance, problems with coordination, anxiety, depression, paranoia, hallucinations, or thoughts about suicide or hurting yourself.

You should not take mefloquine to prevent malaria if you have a recent history of depression, an anxiety disorder, seizures, mental illness (such as schizophrenia), or psychosis.

What is mefloquine?

Mefloquine is a medicine used to treat malaria, a disease caused by parasites. This medicine works by interfering with the growth of parasites in the red blood cells of the human body.

Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

Mefloquine is also used to prevent malaria.

Mefloquine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking mefloquine?

Multum emt

Some people taking mefloquine have had sudden serious psychiatric or nerve problems. Some of these effects have lasted for months to years after mefloquine treatment ended, and these side effects can be permanent. Talk to your doctor if you have concerns about taking mefloquine.

Multum donot

You should not use this medication if you are allergic to mefloquine or similar medications such as quinine or quinidine.

You also should not use mefloquine to prevent malaria if you have a recent history of:

  • depression;
  • an anxiety disorder;
  • seizures; or
  • mental illness (such as schizophrenia) or psychosis.

However, your doctor may prescribe mefloquine to treat malaria even if you do have any of the conditions listed above.

To make sure mefloquine is safe for you, tell your doctor if you have:

  • heart disease;
  • liver disease;
  • epilepsy or other seizure disorder;
  • diabetes;
  • bleeding or blood clotting disorder;
  • a history of mental disease; or
  • if you take a blood thinner (warfarin, Coumadin, Jantoven).

FDA pregnancy category B. It is not known whether mefloquine will harm an unborn baby. Tell your doctor if you are pregnant or if you become pregnant while using this medication. Use effective birth control while you are using this medication and for at least 3 months after your treatment ends.

Multum nobrfeed

Mefloquine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Multum nochild

Mefloquine should not be used to treat malaria in a child younger than 6 months without a doctor's advice. Mefloquine should not be used to prevent malaria in a child who weighs less than 44 pounds.

How should I take mefloquine?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

It is important to use this medication regularly (before, during and after travel) to best prevent malaria. If you stop using the medication early for any reason, talk to your doctor about other forms of malaria prevention.

Multum food

Take mefloquine just after your main meal.

Multum water

Take this medicine with a full glass (8 ounces) of water.

If you have trouble swallowing the mefloquine tablet, you may crush the tablet and mix it into a small glass of milk, water, or other beverage to make swallowing easier.

Multum donot

If you vomit within 30 minutes after taking mefloquine, take another full dose. If you vomit 30 to 60 minutes after taking the medicine, take another half dose. If your vomiting continues, call your doctor.

If you are taking this medicine to prevent malaria:

  • Mefloquine is usually taken once per week to prevent malaria.
  • Start taking the medicine 1 to 3 weeks before entering an area where malaria is common. Continue taking the medicine once weekly during your stay and for at least 4 weeks after you leave the area.
  • Take your weekly dose on the same day each week.
  • If you stop taking the medicine early for any reason, contact a healthcare professional about another form of malaria prevention.

If you are taking mefloquine to treat malaria:

  • Take as directed by your doctor.

In addition to taking mefloquine, use protective clothing, insect repellents, and mosquito netting around your bed to further prevent mosquito bites that could cause malaria.

If you use this medication long-term, you may need frequent blood tests to check your liver function. Your vision may also need to be checked.

Multum calldoc

Contact your doctor as soon as possible if you have been exposed to malaria, or if you have fever or other symptoms of illness during or after a stay in an area where malaria is common.

No medication is 100% effective in treating or preventing malaria. For best results, keep using the medication as directed. Talk with your doctor if you have fever, vomiting, or diarrhea during your treatment.

Multum rt

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since mefloquine is often used as a single dose, you may not be on a dosing schedule. If you are on a weekly schedule, use the missed dose as soon as you remember. Then take the next dose on your next usual dosing day. Do not use extra medicine to make up the missed dose.

Call your doctor for instructions if you forget to take the medicine within 1 week before your travel.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking mefloquine?

Multum donot

Do not take halofantrine or ketoconazole while you are taking mefloquine and for at least 15 weeks after you stop taking it. Serious, life-threatening side effects on your heart can occur if you take halofantrine before the mefloquine has cleared from your body.

Avoid taking chloroquine, quinine, or quinidine while you are taking mefloquine.

Multum dizzy

Mefloquine can cause side effects that may impair your thinking or reactions. Be careful if you drive, operate machinery, pilot an airplane, scuba dive, or do anything that requires you to be awake and alert.

What are the possible side effects of mefloquine?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Stop taking mefloquine and call your doctor right away if you any of these side effects:

  • sudden headache, ringing in your ears, dizziness, loss of balance, or problems with coordination;
  • severe anxiety, depression;
  • paranoia, hallucinations (seeing or hearing things that are not real);
  • confusion, unusual behavior; or
  • thoughts about suicide or hurting yourself.
Multum calldoc

Stop using mefloquine and call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • seizure (convulsions);
  • increased blood pressure --severe headache, blurred vision, chest pain, shortness of breath, uneven heartbeats; or
  • liver problems --nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • stomach pain, vomiting, diarrhea;
  • dizziness;
  • muscle pain;
  • fever, chills; or
  • mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect mefloquine?

Many drugs can interact with mefloquine. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with mefloquine, especially:

  • heart or blood pressure medication;
  • medicine to treat depression or mental illness;
  • seizure medication;
  • tuberculosis medication; or
  • a "live" vaccine such as measles, mumps, and rubella (MMR).

This list is not complete and many other drugs can interact with mefloquine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Where can I get more information?

Your pharmacist can provide more information about mefloquine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2014 Cerner Multum, Inc. Version: 7.01. Revision date: 12/12/2013.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

Last modified on: 21 November 2014


How was your experience with our pharmacy? Click here to tell us!

TTC# 1 and Frustrated/PCOS: Hello Ladies, I am new to the forum and welcome any advice possible. I am 36 years old and have...
40 - First time IVF - Thoughts and Feelings: I am 40 years old, almost 41 and just finished my first round of IVF. The doctor was able to only ta...
Money = Stress: I am 40 years old, almost 41 and just finished my first round of IVF. The doctor was able to only ta...
Other Categories:


Copyright HealthBanks, Inc. All rights reserved. | Terms of Use | Privacy Policy