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mesalamine (oral)

mesalamine (oral)

Pronunciation: me SAL a meen

Brand: Apriso, Asacol, Asacol HD, Delzicol, Lialda, Pentasa

Asacol 400 mg

capsule, red, imprinted with ASACOLNE

Image of Asacol 400 mg
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Pentasa 500 mg

capsule, blue, imprinted with PENTASA 500 mg, LOGO

Image of Pentasa 500 mg
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What is the most important information I should know about mesalamine oral?

Mesalamine is used to treat ulcerative colitis, proctitis, and proctosigmoiditis.

Multum calldoc

Stop using mesalamine and call your doctor at once if you have severe stomach pain, cramping, fever, headache, and bloody diarrhea.

What is mesalamine oral?

Mesalamine affects a substance in the body that causes inflammation, tissue damage, and diarrhea.

Mesalamine is used to treat ulcerative colitis, proctitis, and proctosigmoiditis. Mesalamine is also used to prevent the symptoms of ulcerative colitis from recurring.

Mesalamine may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking mesalamine oral?

Multum donot

You should not use this medication if you are allergic to mesalamine or to aspirin or other salicylates (such as Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others).

To make sure mesalamine is safe for you, tell your doctor if you have:

  • a stomach condition called pyloric stenosis;
  • a history of allergy to sulfasalazine (Azulfidine);
  • heart disease;
  • kidney disease; or
  • liver disease.
Multum nopreg

FDA pregnancy category C. It is not known whether mesalamine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Multum nobrfeed

Mesalamine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I take mesalamine oral?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Multum water

Take mesalamine with a full glass of water.

Multum food

Lialda should be taken with a meal.

Multum icon26

Delzicol on an empty stomach, at least 1 hour before or 2 hours after a meal.

Other brands of mesalamine can be taken with or without food. Follow your doctor's instructions or the directions on your medicine label.

Multum nocrush

Do not crush, break, or chew a mesalamine tablet or capsule. Swallow the pill whole.

The extended-release capsule is specially formulated to release the medicine after it has passed through your stomach into your intestines. Breaking the pill may cause the drug to be released too early in the digestive tract.

The enteric-coated tablet has a special coating to protect your stomach. Breaking the pill could damage this coating.

Call your doctor if you find undissolved tablets in your stool.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are taking mesalamine.

Multum rt

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking mesalamine oral?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of mesalamine oral?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum calldoc

Stop using mesalamine and call your doctor at once if you have:

  • severe stomach pain, cramping, bloody diarrhea;
  • fever, headache, skin rash;
  • chest pain, shortness of breath;
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • little or no urinating;
  • swelling, rapid weight gain; or
  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common side effects may include:

  • mild stomach discomfort, gas, vomiting;
  • diarrhea, constipation;
  • flu symptoms, runny nose;
  • dizziness, weakness; or
  • back pain, joint pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect mesalamine oral?

Other drugs may interact with mesalamine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about mesalamine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2014 Cerner Multum, Inc. Version: 9.04. Revision date: 8/23/2013.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

Last modified on: 21 November 2014


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