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mitotane

mitotane

Pronunciation: MYE toe tane

Brand: Lysodren

Lysodren 500 mg

round, white, imprinted with BL L1

Image of Lysodren 500 mg
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What is the most important information I should know about mitotane?

Multum emt

You may receive your first few doses of mitotane in a hospital setting where you can be monitored in case the medication causes serious side effects.

Multum donot

You should not use this medication if you are allergic to mitotane.

Before taking mitotane, tell your doctor if you have liver disease, or if you have had a recent infection, surgery, or trauma.

Multum nocrush

Always wear rubber gloves when handling mitotane tablets. The medicine from a crushed or broken tablet can be dangerous if it gets on your skin.

You may need to take steroid medication along with mitotane to best treat your condition. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor.

Multum emt

If you have any type of infection, serious injury or medical emergency, you may need to stop taking this medication for a short time. Your doctor will determine when you can start taking mitotane again.

Carry an ID card or wear a medical alert bracelet stating that you are taking mitotane, in case of an emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are using mitotane.

You must remain under the care of a doctor while taking mitotane. Do not miss any scheduled appointments.

Multum finish

It may take up to several months of using mitotane before your symptoms improve. Talk with your doctor if your symptoms do not improve or if they get worse.

What is mitotane?

Mitotane is a cancer medication. That interferes with the growth of cancer cells and slows their growth and spread in the body.

Mitotane is used to treat cancer of the adrenal gland (adrenal cortical carcinoma).

Mitotane may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking mitotane?

Multum donot

You should not use this medication if you are allergic to mitotane.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

  • recent infection, surgery, or trauma;
  • liver disease.
Multum nopreg

FDA pregnancy category C. It is not known whether mitotane is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

Multum nobrfeed

It is not known whether mitotane passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take mitotane?

Multum emt

You may receive your first few doses of mitotane in a hospital setting where you can be monitored in case the medication causes serious side effects.

Take mitotane exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

You may take mitotane with or without food.

Multum nocrush

Always wear rubber gloves when handling mitotane tablets. Do not crush or break a tablet, or use a tablet that has been accidentally broken. The medicine from a crushed or broken tablet can be dangerous if it gets on your skin. If skin contact occurs, wash the area with soap and water. Ask your doctor or pharmacist how to safely dispose of the broken tablet.

Your doctor may occasionally change your dose to make sure you get the best results from this medication. You may also need to take steroid medication to best treat your condition. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor.

Contact your doctor at once if you develop signs of infection such as fever, chills, sore throat, flu symptoms, loss of appetite, nausea and vomiting, mouth sores, or unusual weakness.

Multum emt

If you have any type of infection, serious injury or medical emergency, you may need to stop taking this medication for a short time. Your doctor will determine when you can start taking mitotane again.

Carry an ID card or wear a medical alert bracelet stating that you are taking mitotane, in case of an emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are using mitotane.

To be sure this medication is helping your condition and is not causing harmful effects, your doctor will need to check your progress on a regular basis. You must remain under the care of a doctor while taking mitotane. Do not miss any scheduled appointments.

Multum finish

It may take up to several months of using mitotane before your symptoms improve. For best results, keep using your medications as directed. Talk with your doctor if your symptoms do not improve or if they get worse.

Multum rt

Store mitotane at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a mitotane overdose are not known.

What should I avoid while taking mitotane?

Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.

Avoid activities that may increase your risk of trauma or injury.

Multum dizzy

Mitotane can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What are the possible side effects of mitotane?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Call your doctor at once if you have a serious side effect such as:

  • feeling like you might pass out;
  • fast or pounding heartbeats;
  • warmth, redness, or tingly feeling under your skin;
  • sweating, cold or clammy skin;
  • high fever, chills, uncontrolled shaking;
  • blurred or double vision;
  • confusion, problems with speech, balance, or walking;
  • pain or burning when you urinate;
  • blood in your urine; or
  • unexpected weight loss.

Less serious side effects may include:

  • dizziness, spinning sensation;
  • drowsiness, tired feeling;
  • depressed mood;
  • mild skin rash;
  • nausea, vomiting, diarrhea; or
  • loss of appetite.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect mitotane?

Multum dizzy

Before using mitotane, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by mitotane.

Tell your doctor about all other medications you use, especially:

  • a blood thinner such as warfarin (Coumadin);
  • spironolactone (Aldactone).

This list is not complete and there may be other drugs that can interact with mitotane. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about mitotane.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2013 Cerner Multum, Inc. Version: 3.02. Revision date: 12/15/2010.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

Last modified on: 2 April 2014


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