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glipizide and metformin

glipizide and metformin

Pronunciation: GLIP ih zyd and met FOR min

Brand: Metaglip

Glipizide-Metformin 2.5 mg-250 mg-TEV

oval, pink, imprinted with 93, 7455

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Glipizide-Metformin 2.5 mg-500 mg-TEV

oval, white, imprinted with 93, 7456

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Glipizide-Metformin 5 mg-500 mg-MYL

oval, orange, imprinted with M, G33

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Glipizide-Metformin 2.5 mg-250 mg-MYL

round, white, imprinted with G31, M

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Glipizide-Metformin 2.5 mg-500 mg-MYL

oval, white, imprinted with M, G32

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Metaglip 2.5 mg-250 mg

oval, pink, imprinted with BMS, 6081

Image of Metaglip 2.5 mg-250 mg
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Glipizide-Metformin 5 mg-500 mg-TEV

oval, pink, imprinted with 93, 7457

Image of Glipizide-Metformin 5 mg-500 mg-TEV
slide 7 of 9
    

Metaglip 2.5-500 mg

oval, white, imprinted with BMS, 6077

Image of Metaglip 2.5-500 mg
slide 8 of 9
    

Metaglip 5-500 mg

oval, pink, imprinted with BMS, 6078

Image of Metaglip 5-500 mg
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What is the most important information I should know about glipizide and metformin?

Multum donot

You should not use glipizide and metformin if you have kidney disease, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

Multum emt

Some people taking metformin develop a serious condition called lactic acidosis. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired.

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking glipizide and metformin.

What is glipizide and metformin?

Glipizide and metformin is a combination of two oral diabetes medicines that help control blood sugar levels.

Glipizide and metformin is for people with type 2 diabetes who do not use daily insulin injections. This medication is not for treating type 1 diabetes.

Glipizide and metformin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking glipizide and metformin?

Multum donot

You should not use this medicine if you are allergic to glipizide or metformin, or if you have:

  • kidney disease; or
  • if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking glipizide and metformin.

To make sure glipizide and metformin is safe for you, tell your doctor if you have:

  • congestive heart failure, especially if you take digoxin (Lanoxin) or furosemide (Lasix);
  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency;
  • liver disease;
  • heart disease; or
  • if you are over 80 years old and have not recently had your kidney function checked.
Multum emt

Some people taking metformin develop a serious condition called lactic acidosis. This may be more likely if you have liver or kidney disease, congestive heart failure, heart attack or stroke, a severe infection, if you are dehydrated, or if you drink large amounts of alcohol. Talk with your doctor about your risk.

Multum nopreg

FDA pregnancy category C. It is not known whether glipizide and metformin will harm an unborn baby. Similar diabetes medications have caused severe hypoglycemia in newborn babies whose mothers had used the medication near the time of delivery. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

Multum nobrfeed

It is not known whether glipizide and metformin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking this medicine.

How should I take glipizide and metformin?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Multum food

Take glipizide and metformin with meals.

Multum calldoc

Call your doctor if you are sick with vomiting, diarrhea, or a fever. These conditions can lead to severe dehydration, which could be dangerous while you are taking glipizide and metformin.

Multum water

Drink plenty of liquids while you are taking glipizide and metformin.

Multum dizzy

Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, confusion, irritability, dizziness, or feeling shaky. Always keep a source of sugar with you in case you have low blood sugar. Sugar sources include fruit juice, hard candy, crackers, raisins, and non-diet soda. Be sure your family and close friends know how to help you in an emergency.

If you have severe hypoglycemia and cannot eat or drink, use a glucagon injection. Your doctor can prescribe a glucagon emergency injection kit and tell you how to use it.

Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

Multum donot

Check your blood sugar carefully during times of stress, travel, illness, surgery or medical emergency, vigorous exercise, or if you drink alcohol or skip meals. These things can affect your glucose levels and your dose needs may also change. Do not change your medication dose or schedule without your doctor's advice.

Your doctor may have you take extra vitamin B12 while you are taking glipizide and metformin. Take only the amount of vitamin B12 that your doctor has prescribed.

Glipizide and metformin is only part of a treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Multum rt

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember (be sure to take the medicine with food). Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause life-threatening hypoglycemia.

Symptoms of severe hypoglycemia include extreme weakness, confusion, tremors, sweating, fast heart rate, trouble speaking, nausea, vomiting, rapid breathing, fainting, and seizure (convulsions).

Overdose may also cause lactic acidosis symptoms such as muscle pain, numbness, trouble breathing, vomiting, slow heart rate, and extreme weakness.

What should I avoid while taking glipizide and metformin?

Multum noalcohol

Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.

If you also take colesevelam, avoid taking it within 4 hours after you take glipizide and metformin.

What are the possible side effects of glipizide and metformin?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Multum emt

Some people develop lactic acidosis while taking metformin. Early symptoms may get worse over time and this condition can be fatal. Stop taking this medicine and get emergency medical help if you have even mild symptoms such as:

  • muscle pain or weakness;
  • numb or cold feeling in your arms and legs;
  • trouble breathing;
  • feeling dizzy, light-headed, tired, or very weak;
  • stomach pain, nausea with vomiting; or
  • slow or uneven heart rate.
Multum calldoc

Call your doctor at once if you have:

  • swelling, rapid weight gain; or
  • shortness of breath (even with mild exertion).

Common side effects may include:

  • upset stomach, nausea, diarrhea;
  • headache; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect glipizide and metformin?

There are many other medicines that can increase or decrease the effects of glipizide and metformin on lowering your blood sugar. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about glipizide and metformin.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2014 Cerner Multum, Inc. Version: 8.01. Revision date: 5/27/2014.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

Last modified on: 21 November 2014


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