DesignRx delivers pharmacy value and service
for your specialty medication needs
  Home  
  Counseling  
  Compounding  
  How to Order  
  Contact Us  

News for Healthier Living

Arthritis in Children Linked to Infections

TUESDAY, May 1 (HealthDay News) -- Children with juvenile arthritis have higher rates of bacterial infection when hospitalized than children without arthritis, a new study says.

While taking high-dose steroids was associated with a higher infection risk among kids with arthritis, other arthritis drugs -- methotrexate and tumor necrosis factor alpha (TNF) inhibitors -- were not.

Researchers analyzed Medicaid data on nearly 8,500 children with juvenile idiopathic arthritis and more than 360,000 arthritis-free children. Idiopathic means that a disease occurs without a known cause.

Pharmacy claims were examined to determine arthritis patients' use of drugs that suppress the immune system, including high-dose glucocorticoids (steroids), methotrexate and TNF inhibitors, according to the study published May 1 in the journal Arthritis & Rheumatism.

Kids with arthritis who were not currently treated with methotrexate or TNF inhibitors had a 2-fold increase in bacterial infection rates while hospitalized compared to children without arthritis, study leader Dr. Timothy Beukelman, of the University of Alabama at Birmingham, said in a journal news release. "This finding suggests the inflammatory or autoimmune process may predispose children to infection regardless of therapy," Beukelman said.

Among children with juvenile arthritis, the rate of infection associated with methotrexate or TNF inhibitor treatment was similar.

After they adjusted for methotrexate and TNF inhibitor use among the arthritis patients, the researchers found that the rate of bacterial infection among those who took high-dose steroids (10 milligrams or more of prednisone a day) was more than twice that of those who did not take steroids.

Limiting steroids may reduce the risk of serious infection in children with arthritis, Beukelman concluded.

Nearly 300,000 children in the United States have juvenile idiopathic arthritis, according to the American College of Rheumatology.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about juvenile arthritis.

May 1, 2012
Copyright © 2012 HealthDay. All rights reserved.


August 4 2015

August 3 2015

August 2 2015

August 1 2015

July 31 2015

July 30 2015

July 29 2015

July 28 2015

July 27 2015

July 26 2015

July 25 2015

July 24 2015

July 23 2015

July 22 2015

July 21 2015


How was your experience with our pharmacy? Click here to tell us!

Single 37yo freezing my eggs (not embryos). Anyone else?: I hope that you are better now, see that after the second round, you don't have any other complicati...
40 - First time IVF - Thoughts and Feelings: Congrats to all the newly pregnant ladies! I'm starting the process. My meds are done, and Friday I ...
IVF journey: Hi Ladies, First, I would like to congratulate everyone who is pregnant! Many blessings to you, your...
Other Categories:


Copyright HealthBanks, Inc. All rights reserved. | Terms of Use | Privacy Policy