News for Healthier Living

Dual Functions of PME-1 Protein Critical for Brain Development and Disease Treatment

A study in The FASEB Journal reveals PME-1 protein regulates tumor suppressor PP2A through two distinct mechanisms: methyl group removal and direct binding. Using genetically modified mice, researchers found each function affects different developmental aspects--demethylation impacts brain development while binding affects olfaction.

May 13, 2025


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