News for Healthier Living

Hydrogel Innovation Offers Hope for Dry Mouth Treatment

Millions suffer from xerostomia, or dry mouth--a painful condition often caused by cancer treatments or autoimmune disease. Now, scientists have developed a smart hydrogel system that mimics the native salivary gland environment, enabling human salivary cells to grow and function in three-dimensional (3D) spheroids. Built from a blend of hyaluronic acid, alginate, and gelatin, the matrix supports the expansion and organization of acinar cells, the key fluid-producing units of the gland. These lab-grown spheroids not only remain viable and structurally intact over two weeks but also demonstrate real functional activity, responding to biochemical signals much like their natural counterparts. The innovation marks a leap forward in tissue modeling and potential regenerative therapies.

May 30, 2025


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