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Not So Sweet: Some Sugar Substitutes Linked to Faster Cognitive Decline

Some sugar substitutes may come with unexpected consequences for long-term brain health, according to a study published in the September 3, 2025, issue of Neurology(r), the medical journal of the American Academy of Neurology. The study examined seven low- and no-calorie sweeteners and found that people who consumed the highest amounts experienced faster declines in thinking and memory skills compared to those who consumed the lowest amounts. The link was even stronger in people with diabetes. While the study showed a link between the use of some artificial sweeteners and cognitive decline, it did not prove that they were a cause.

September 3, 2025


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Angell Street Psychiatry
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