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Long Noncoding RNA LOC646029 Functions as a ceRNAto Suppress Ovarian Cancer Progression Through the miR-627-3p/SPRED1 Axis

This study found lncRNA LOC646029 was downregulated in metastatic ovarian tumors (linked to poor prognosis), showed it inhibits ovarian cancer cell proliferation/invasiveness/metastasis by sponging miR-627-3p to boost SPRYEVH1 (suppressing metastasis/KRAS signaling), suggesting it's involved in ovarian cancer progression and a potential prognostic biomarker.

September 17, 2025


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Angell Street Psychiatry
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