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News for Healthier Living

Bias Can Lead to Better Therapies

Scientists at Sanford Burnham Prebys, the University of Minnesota and Duke University published findings October 22, 2025, in Nature demonstrating how a small molecule can bind a G protein-coupled receptor on the inside of the cell and bias or more specifically direct the receptor's signaling. If drug designers can control how compounds bias signaling, they can leverage those that favor therapeutic pathways while preventing changes in other pathways that result in unwanted side effects.

October 22, 2025


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