News for Healthier Living

Arginine Methylation of ALKBH5 by PRMT6 Promotes Breast Tumorigenesis via LDHA-Mediated Glycolysis

This paper demonstrates that PRMT6 promotes breast tumor growth by methylating ALKBH5, which enhances LDHA RNA stability via m6A demethylation to increase aerobic glycolysis, identifying a PRMT6-ALKBH5-LDHA axis as a therapeutic target.

October 31, 2025


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