News for Healthier Living

Aligning Genomic Data and Real-World Clinical Health Records Identifies Medications That Could Potentially Be Repurposed for Treating Alcohol Use Disorder

A novel approach has identified drugs in current use that could be repurposed for treating alcohol use disorder (AUD). In 2023, 28 million US adults had experienced AUD in the past year. But only three medications are approved by the FDA to treat the condition. Those drugs have uneven effectiveness, and health care providers' lack of familiarity with them contributes to low use. The cost of developing a new drug is $1-3 billion, but repurposing other medications with known safety profiles--a route that historically relied on clinical observation and chance discoveries--would be dramatically less expensive. The increasing availability of large databanks facilitates computational approaches that can efficiently screen for promising medication uses.

March 11, 2026


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