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News for Healthier Living

Additional Nerve Blocks Show Minimal Impact on Worst Postoperative Pain but Reduce Opioid Consumption in Knee Replacement Patients

Adding two additional nerve blocks to a standard multimodal pain regimen for total knee replacement did not significantly reduce worst pain in the recovery room or total opioid use in the first 24 hours, based on a clinical trial conducted at the Hospital for Special Surgery in New York, NY. The study supports the hypothesis that, while the extra blocks may have some benefits, the standard regimen remains highly effective for most patients.

March 27, 2026


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