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RAS Inhibitor Daraxonrasib Demonstrates Initial Anti-Tumor Activity in Pancreatic Cancer

Daraxonrasib is an oral, multi-selective RAS inhibitor from Revolution Medicines Data from this trial previously prompted the Food and Drug Administration (FDA) to grant orphan drug designation to daraxonrasib and the Phase 3 RASolute trial Therapy is being investigated in pancreatic cancer because of the high prevalence of RAS mutations and lack of effective therapies The targeted RAS inhibitor therapy daraxonrasib demonstrated the potential to improve patient outcomes over current standard treatments for patients with RAS-mutant pancreatic cancer, according to results of a Phase 1/2 trial led by researchers at The University of Texas MD Anderson Cancer Center.

May 6, 2026


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