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News for Healthier Living

Future Cancer Therapy Could Use Immunity to Clean Up Damaged DNA by Modulating AUF1

Researchers have identified a pathway that triggers an immune response in cells with defective DNA repair. In particular, the authors of a new paper demonstrated how the downregulation of AUF1 impairs DNA repair, followed by activation of the immune response due to the presence of R-loops in the cytoplasm.

May 12, 2026


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