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Most Cases of HIV Persistence in Blood Following Treatment Explained by Defective Copies of the Virus

Antiretroviral drugs for HIV infection have enabled most people living with the virus to live long and healthy lives. However, a small portion of people experience detectable and worrisome traces of the virus that causes AIDS despite strict adherence to long-term treatment regimens and the absence of symptoms. New findings in Nature Communications suggest that most cases of this phenomenon (non-suppressible viremia) are explained by defective and noninfectious copies of the virus.

June 8, 2026


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