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News for Healthier Living

Recurrence-Associated eccDNA Features Provide New Prognostic Insights Into Lung Adenocarcinoma

A multi-omics study has revealed distinct extrachromosomal circular DNA (eccDNA) features associated with postoperative recurrence in lung adenocarcinoma (LUAD). By integrating Circle-seq with genomic, transcriptomic, epigenomic, and clinical data, the researchers characterized recurrence-associated eccDNA profiles and identified a seven-gene signature with potential value for recurrence risk stratification.

August 10, 2026


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