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Menthol Enhances the Strength, Duration of Nicotine's Effects in Rats

Menthol, a common flavoring for both traditional cigarettes and e-cigarettes, may do more than simply change how nicotine tastes or feels. New research published in ACS Chemical Neuroscience reports that male rats exposed to menthol-containing e-cigarette aerosols experienced nicotine's effects more strongly and for longer than rats exposed to nicotine alone. The findings provide insight into how menthol can modify the effects of inhaled nicotine.

September 29, 2026


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